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Balboa park Botanical Building and pond, San Diego, California, United States

San Diego: Southern California residents know they have it good: Close to 356 days of sunshine a year, moderate temperatures and gorgeous beaches await visitors. Beer nerds -- especially West Coast hop lovers -- will delight in the thriving craft-brewery scene. The pace is decidedly relaxed, but there's still plenty to keep visitors occupied for a long weekend. The San Diego Zoo is not to be missed.