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Doctor Strange in the Multiverse of Madness is an upcoming 2022 American superhero film based on the Marvel Comics character Doctor Strange. Produced by Marvel Studios and distributed by Walt Disney Studios Motion Pictures, it is intended to be the sequel to Doctor Strange (2016) and the 28th film of the Marvel Cinematic Universe (MCU). The film is directed by Sam Raimi from a script written by Jade Halley Bartlett and Michael Waldron, and stars Benedict Cumberbatch as Stephen Strange, alongside Benedict Wong, Rachel McAdams, Chiwetel Ejiofor, Elizabeth Olsen, and Xochitl Gomez. In the film, Strange unleashes an unspeakable evil as he faces a friend-turned-enemy.

Doctor Strange director and co-writer Scott Derrickson had plans for a sequel by October 2016. He signed to return as director in December 2018, when Cumberbatch was confirmed to return. The film's title was announced in July 2019 along with Olsen's involvement, while Bartlett was hired to write the film that October. Derrickson stepped down as director in January 2020, citing creative differences. The next month, Waldron joined the project, and Raimi took over as director by April 2020. Filming began in November 2020 in London but was put on hold in January 2021 due to the COVID-19 pandemic. Production resumed by March 2021 and concluded in mid-April in Somerset. Shooting also occurred in Surrey and Los Angeles.

Doctor Strange in the Multiverse of Madness is scheduled to be released in the United States on May 6, 2022, as part of Phase Four of the MCU.