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Resident Evil is an upcoming horror film directed by Zach Cregger, who co-wrote the screenplay with Shay Hatten. It is the second reboot of the Resident Evil film series, based on Capcom's Resident Evil video game franchise. The film, set in modern times, during the alternate events of Resident Evil 2 (1998), follows Bryan (Austin Abrams), a medical courier who is caught in a viral outbreak of infected monsters in Raccoon City and has to fight for survival. Zach Cherry, Kali Reis, Johnno Wilson and Paul Walter Hauser feature in supporting roles.

Constantin Film began planning another Resident Evil reboot in early 2022, following the critical and commercial failure of Resident Evil: Welcome to Raccoon City (2021) and the cancellation of the 2022 Netflix television series. Cregger was hired to direct in January 2025, and Sony Pictures' PlayStation Productions joined the production. Four studios, including Warner Bros. Pictures and Netflix, bid for distribution rights, with Sony's Columbia Pictures winning in March. Filming began in October 2025 in Prague.

Resident Evil is scheduled to be released on September 18, 2026.